| Hardware and OS | Vivo V21 SE | |
| Operating system | Android v10 (Q) | |
| Processor | Qualcomm Snapdragon 665 | |
| RAM | 8 GB | |
| Internal Storage | 128 GB | |
| Expandable memory | Yes, Upto 512 GB | |
| Display | Vivo V21 SE | other phones |
| Type | IPS LCD | |
| Size | 6.44 inches | |
| Resolution | 1080 x 2400 Pixels | |
| Pixel Density | 409 ppi | |
| Touchscreen | Yes, Capacitive Touchscreen, Multi-touch | |
| Connectivity | Vivo V21 SE | other phones |
| Network support | 4G , 3G, 2G | |
| WI-FI | Yes, Wi-Fi 802.11, b/g/n | |
| Gps | Yes, with A-GPS | |
| Bluetooth | Yes, v5.0 | |
| Dual SIM | Dual SIM, GSM GSM | |
| SIM size | SIM1: Nano, SIM2: Nano (Hybrid) | |
| USB TYPE-C | Yes | |
| USB connectivity | Mass storage device, USB charging | |
| Camera | Vivo V21 SE | other phones |
| Image | 8000 x 6000 Pixels | |
| Front camera resolution | 32 MP, Wide Angle Primary Camera | |
| Camera features | Digital Zoom, Auto Flash, Face detection, Touch to focus | |
| Flash | Yes, LED Flash | |
| Autofocus | Yes | |
| Video recording | Yes | |
| Multimedia | Vivo V21 SE | other phones |
| Audio jack | 3.5 MM | |
| Loudspeaker | Yes | |
| Design | Vivo V21 SE | other phones |
| Colours | Black | |
| Battery | Vivo V21 SE | other phones |
| Capacity | 4200 mAh | |
| Type | Li-ion | |
| User replaceable | No | |
| Quick charging | Yes, Fast | |
| Other | Vivo V21 SE | other phones |
| Fingerprint sensor | Yes | |
| Fingerprint sensor position | On-Screen | |
| Other sensors | Light sensor, Proximity sensor, Accelerometer, Compass | |