| Hardware and OS | vivo iQOO Neo5 S | |
| Operating system | Android 11, Origin OS Ocean | |
| Processor | Octa-core (1x2.84 GHz Kryo 680 & 3x2.42 GHz Kryo 680 & 4x1.80 GHz Kryo 680) | |
| Chipset | Qualcomm SM8350 Snapdragon 888 5G (5 nm) | |
| GPU | Adreno 660 | |
| Internal memory | 128GB 8GB RAM, 256GB 8GB RAM, 256GB 12GB RAM | |
| External memory | No | |
| Display | vivo iQOO Neo5 S | other phones |
| Type | AMOLED, 120Hz, HDR10 , 1300 nits (peak) | |
| Size | 6.62 inches, 105.8 cm2(~84.9% screen-to-body ratio) | |
| Resolution | 1080 x 2400 pixels, 20:9 ratio | |
| Colors | Orange, Blue, Black | |
| Design | vivo iQOO Neo5 S | other phones |
| SIM | Dual SIM (Nano-SIM, dual stand-by) | |
| Dimensions | 163.2 x 76.4 x 8.4 mm (6.43 x 3.01 x 0.33 in) | |
| Weight | 196 g (6.91 oz) | |
| Connectivity | vivo iQOO Neo5 S | other phones |
| 2G Network | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 | |
| 3G Network | HSDPA 850 / 900 / 1900 / 2100 | |
| 4G Network | 1, 3, 4, 5, 8, 28, 34, 38, 39, 40, 41 | |
| 5G Network | 1, 3, 5, 8, 28, 41, 77, 78 SA/NSA | |
| WLAN | Wi-Fi 802.11 a/b/g/n/ac/6, dual-band, Wi-Fi Direct, hotspot | |
| Bluetooth | 5.2, A2DP, LE, aptX HD, aptX Adaptive | |
| GPS | Yes, with A-GPS, GLONASS, GALILEO, BDS, QZSS | |
| NFC | Yes | |
| USB | USB Type-C 2.0, USB On-The-Go | |
| CDMA | CDMA 800 | |
| Speed | HSPA 42.2/5.76 Mbps, LTE-A, 5G | |
| Technology | GSM / CDMA / HSPA / CDMA2000 / LTE / 5G | |
| Main Camera | vivo iQOO Neo5 S | other phones |
| Camera | 48 MP, f/1.8, 25mm (wide), 1/2.0", 0.8??m, PDAF, OIS
13 MP, f/2.2, 16mm, 120?? (ultrawide)
2 MP, f/2.4, (macro) | |
| Features | Dual-LED dual-tone flash, HDR, panorama | |
| Video | 4K@30fps, 1080p@30fps | |
| Selfie camera | vivo iQOO Neo5 S | other phones |
| Camera | 16 MP, f/2.0, (wide) | |
| Features | HDR | |
| Video | 1080p@30fps | |
| Multimedia | vivo iQOO Neo5 S | other phones |
| Radio | No | |
| Multimedia | 24-bit/192kHz audio | |
| 3.5 mm Jack | No | |
| Loudspeaker | Yes, with stereo speakers | |
| Features | vivo iQOO Neo5 S | other phones |
| Sensors | Fingerprint (under display, optical), accelerometer, gyro, proximity, compass | |
| Battery | vivo iQOO Neo5 S | other phones |
| Type | Li-Po 4500 mAh, non-removable | |
| Charging | Fast charging 66W, 70% in 18 min (advertised) | |
