| Hardware and OS | Oppo Reno4 SE 5G | |
| Operating system | Android v10 (Q) | |
| Custom UI | ColorOS | |
| Processor | Octa core (2 GHz, Quad core, Cortex A76 2 GHz, Quad core, Cortex A55) | |
| Chipset | MediaTek Dimensity 800 MT6873V | |
| Internal Storage | 128 GB | |
| Expandable memory | No | |
| GPU | Mali-G57 MC4 | |
| RAM | 8 GB | |
| Camera | Oppo Reno4 SE 5G | other phones |
| Main camera | 48 MP 8 MP 2 MP | |
| Aperture | F2.4 | |
| Autofocus | Yes | |
| Camera features | Digital Zoom, Auto Flash, Face detection, Touch to focus | |
| Image | 8000 x 6000 Pixels | |
| Flash | Yes, LED Flash | |
| Front camera | 32 MP | |
| Front camera resolution | 32 MP f/2.4 Primary Camera | |
| Video recording | Yes | |
| Connectivity | Oppo Reno4 SE 5G | other phones |
| Bluetooth | Yes, v5.0 | |
| SIM size | SIM1: Nano, SIM2: Nano | |
| Dual SIM | Dual SIM, GSM GSM | |
| GPS | Yes, with A-GPS, Glonass | |
| Network support | 5G , 4G , 3G, 2G | |
| NFC | Yes | |
| USB connectivity | Mass storage device, USB charging | |
| USB TYPE-C | Yes | |
| WI-FI | Yes, Wi-Fi 802.11, ac/b/g/n/n 5GHz | |
| Multimedia | Oppo Reno4 SE 5G | other phones |
| Audio jack | 3.5 MM | |
| Loudspeaker | Yes | |
| Battery | Oppo Reno4 SE 5G | other phones |
| Capacity | 4300 mAh | |
| Type | Li-ion | |
| User replaceable | No | |
| Quick charging | Yes, VOOC, v2.0, 65W | |
| Design | Oppo Reno4 SE 5G | other phones |
| Height | 160.5 mm | |
| Width | 73.9 mm | |
| Thickness | 7.85 mm | |
| Weight | 169 grams | |
| Features | Oppo Reno4 SE 5G | other phones |
| Fingerprint sensor position | On-Screen | |
| Fingerprint sensor | Yes | |
| Other sensors | Light sensor, Proximity sensor, Accelerometer, Compass, Gyroscope | |