| Hardware and OS | OPPO F21s Pro | |
| Operating system | Android v12 | |
| Processor | 2.2 GHz, Octa Core Processor | |
| Chipset | Qualcomm Snapdragon 695 | |
| Cores | 2x2.2 GHz Kryo 660 Gold & 6x1.7 GHz Kryo 660 Silver | |
| GPU | Adreno 619 | |
| Ram | 8 GB | |
| Storage | 128 GB | |
| Card Slot | Yes, upto 512 GB | |
| Display | OPPO F21s Pro | other phones |
| Size | 6.43 inches, 1080 x 2400 pixels, 60 Hz | |
| Type | Color AMOLED Screen (16.7M) | |
| Aspect Ratio | 20:9 | |
| Glass Type | Corning Gorilla Glass | |
| PPI | ~409 PPI | |
| Screen to Body Ratio | ~ 90.8% | |
| Touch | Yes, with Multitouch | |
| Features | 180Hz touch Sampling Rate, 600 nits, 97% NTSC/93% DCI-P3 Gentle mode | |
| Main Camera | OPPO F21s Pro | other phones |
| Camera | Punch Hole 16 MP f/2.4 | |
| Flash | Yes, LED | |
| Features | Night, Photo, Video, PRO, PANO, Portrait, TIME-LAPSE, SLO-MO, Text scanner, Google Lens, Extra HD, Macro, STICKER, and Dual-view video | |
| Video | 1080p | |
| Selfie camera | OPPO F21s Pro | other phones |
| Camera | 64 MP f/1.7 (Wide Angle)
2 MP f/2.4 (Microscope)
2 MP f/2.4 (Mono) with autofocus | |
| Video | 1080p, 720p | |
| Connectivity | OPPO F21s Pro | other phones |
| 3G Network | Yes | |
| 4G Network | Yes | |
| 5G Network | Yes | |
| Bluetooth | Yes, v5.1 | |
| EDGE | Yes | |
| GPRS | Yes | |
| GPS | Built-in GPS, A-GPS, BeiDou, GLONASS, Galileo, QZSS | |
| USB | Yes, USB-C | |
| USB Features | USB on-the-go, USB Charging | |
| VoLTE | Yes, Dual Stand-By | |
| Wifi | Yes, with wifi-hotspot | |
| Multimedia | OPPO F21s Pro | other phones |
| 3.5 mm Jack | Yes | |
| Battery | OPPO F21s Pro | other phones |
| Type | Non-Removable Battery | |
| Battery capacity | 4500 mAh, Li-Po Battery | |
| Fast Charging | Yes, 33W Fast Charging | |
| Design | OPPO F21s Pro | other phones |
| Dimensions | 73.2 x 159.9 x 7.66 mm | |
| Weight | 181 g | |
| Dual Sim | Yes | |
| Sim Type | Dual Sim, GSM GSM | |
| Sim Size | Nano Nano SIM | |
| Features | OPPO F21s Pro | other phones |
| Sensors | Geomagnetic Sensor, Proximity Sensor, Optical Sensor, Accelerometer, Gravity Sensor, Gyroscope, Pedometer, Compass | |
| Fingerprint Sensor | Yes, In Display | |
| Face Unlock | Yes | |
