| Hardware and OS | HTC U21 Plus | |
| Operating system | Android v11 | |
| Processor | Qualcomm SDM765 Snapdragon 765G (7 nm) | |
| RAM | 8 GB | |
| Internal Storage | 256 GB | |
| Display | HTC U21 Plus | other phones |
| Type | IPS LCD | |
| Size | 6.8 inches | |
| Resolution | 1080 x 2400 Pixels | |
| Pixel Density | 378 ppi | |
| Touchscreen | Yes, Capacitive Touchscreen, Multi-touch | |
| Connectivity | HTC U21 Plus | other phones |
| Network support | 5G , 4G , 3G, 2G | |
| WI-FI | Yes, Wi-Fi 802.11, b/g/n | |
| Gps | Yes, with A-GPS, Glonass | |
| Bluetooth | Yes, v5.0 | |
| NFC | Yes | |
| Dual SIM | Dual SIM, GSM GSM | |
| SIM size | SIM1: Nano, SIM2: Nano | |
| USB connectivity | Mass storage device, USB charging | |
| Camera | HTC U21 Plus | other phones |
| Main camera | 48 MP 8 MP 2 MP 2 MP | |
| Front camera | 32 MP | |
| Front camera resolution | 32 MP, f/2.0, (wide) | |
| Camera features | Digital Zoom, Auto Flash, Face detection, Touch to focus | |
| Flash | Yes, Dual LED Flash | |
| Autofocus | Yes | |
| Video recording | Yes | |
| Multimedia | HTC U21 Plus | other phones |
| Audio jack | 3.5 MM | |
| Loudspeaker | Yes | |
| Design | HTC U21 Plus | other phones |
| Height | 171.2 mm | |
| Width | 78.1 mm | |
| Thickness | 9.4 mm | |
| Weight | 251.5 grams | |
| Colours | Green, White | |
| Battery | HTC U21 Plus | other phones |
| Capacity | 5000 mAh | |
| Type | Li-Polymer | |
| Other | HTC U21 Plus | other phones |
| Fingerprint sensor | Yes | |
| Fingerprint sensor position | Rear | |
| Other sensors | Accelerometer, Gyro, Proximity, Compass | |
