| Hardware and OS | HTC U | |
| Operating System | Android v7.0 (Nougat) | |
| Processor | 2.45 GHz, Octa Core Processor | |
| Chipset | Qualcomm Snapdragon 835 | |
| RAM | 6 GB | |
| Internal Memory | 128 GB | |
| Memory Card Slot | Yes | |
| Graphics | Adreno 540 | |
| Dual Sim | No | |
| Sim Size | Nano SIM | |
| Sim Type | Single Sim, GSM | |
| Display | HTC U | other phones |
| Screen Size | 5.5 inches, 1440 x 2560 pixels | |
| Display Type | Color LCD screen (16M colors) | |
| Pixel Density | ~534 PPI | |
| Touch Screen | Yes, with Multitouch | |
| Display aspect ratio | 16:9 | |
| Features | Corning Gorilla Glass 4 Screen Protection | |
| Connectivity | HTC U | other phones |
| 3G Network | Yes | |
| 4G Network | Yes | |
| Bluetooth | Yes, v4.2 | |
| EDGE | Yes | |
| GPRS | Yes | |
| USB | Yes v3.1 | |
| Wifi | Yes, with wifi-hotspot | |
| Multimedia | HTC U | other phones |
| Email | Yes, with Push Email | |
| FM Radio | No | |
| Music | MP3, eAAC , WMA, WAV, FLAC | |
| Video | XviD, MP4, H.264, WMV | |
| Browser | Yes, supports HTML | |
| Java | No | |
| Supports | MMS | |
| Battery | HTC U | other phones |
| Battery capacity | Li-ion Battery | |
| Type | Non-Removable Battery | |
| Other | HTC U | other phones |
| Sensors | Accelerometer, Gyroscope, Compass | |
| Fingerprint Sensor | Yes | |
| Features | Face detection, Geo tagging, Panorama, Touch to focus | |
