| Hardware and OS | HTC Desire 650 | |
| Operating system | Android 6.0 (Marshmallow); Sense UI | |
| Processor | Quad-core 1.6 GHz Cortex-A7 | |
| Chipset | Qualcomm MSM8928 Snapdragon 400 (28 nm) | |
| GPU | Adreno 305 | |
| Internal memory | 16 GB, 2 GB RAM | |
| External memory | microSD, up to 256 GB (dedicated slot) | |
| Display | HTC Desire 650 | other phones |
| Type | IPS LCD | |
| Size | 5" inc | |
| Resolution | 720 x 1280 px | |
| Protection | Corning Gorilla Glass (unspecified version) | |
| Touchscreen | capacitive touchscreen | |
| Screen-to-Body Ratio | 66.2% | |
| Display area | 68.9 cm2 | |
| Display aspect ratio | 16:9 (height:width) | |
| Pixel Density | 294 PPI | |
| Colors | 16M | |
| Connectivity | HTC Desire 650 | other phones |
| 2G Network | GSM 850 / 900 / 1800 / 1900 - SIM 1 & SIM 2 (dual-SIM model only) | |
| 3G Network | HSDPA 850 / 900 / 1700(AWS) / 1900 / 2100 | |
| 4G Network | LTE band 1(2100), 2(1900), 3(1800), 4(1700/2100), 5(850), 7(2600), 8(900), 20(800), 28(700), 38(2600) | |
| Wi-Fi | Wi-Fi 802.11 b/g/n, hotspot | |
| Network | GSM / HSPA / LTE | |
| SIM card | Single SIM (Nano-SIM)Dual SIM (Nano-SIM, dual stand-by) | |
| Bluetooth | 4.1, A2DP, LE | |
| Edge | Yes | |
| GPRS | Yes | |
| GPS | Yes, with A-GPS, GLONASS | |
| NFC | Yes (EMEA only) | |
| Speed | HSPA, LTE Cat4 150/50 Mbps | |
| USB | microUSB 2.0 | |
| Camera | HTC Desire 650 | other phones |
| Main camera | 13 MP, Single | |
| Specs | 13 MP, f/2.0, 28mm (wide), AF | |
| Features | LED flash, HDR, panorama | |
| Video | 1080p@30fps | |
| Selfie camera | 5 MP, Single | |
| Multimedia | HTC Desire 650 | other phones |
| 3.5 mm Jack | Yes | |
| Radio | FM radio | |
| Design | HTC Desire 650 | other phones |
| Colors | Dark blue, White | |
| Dimensions | 146.9 x 70.9 x 8.4 mm | |
| Weight | 140 g | |
| Battery | HTC Desire 650 | other phones |
| Battery capacity | 2200 mAh, Non-removable Li-Ion | |
| Battery life | Stand by time- Up to 684 h (3G)
Talking time- Up to 17 h 30 min (3G)
Music play - Up to 44 h | |
| Other | HTC Desire 650 | other phones |
| Release date | 2016, November | |
| Sensors | Accelerometer, proximity | |
