| Hardware and OS | Honor 80 Pro Plus | |
| Operating system | Android v12 | |
| Processor | 3 GHz, Octa Core Processor | |
| Chipset | Qualcomm Snapdragon 8 Gen1 | |
| Cores | 1x3.00 GHz Cortex-X2 & 3x2.50 GHz Cortex-A710 & 4x1.80 GHz Cortex-A510 | |
| GPU | Adreno 730 | |
| Ram | 12 GB | |
| Storage | 256 GB | |
| Card Slot | No | |
| Display | Honor 80 Pro Plus | other phones |
| Size | 6.78 inches, 1200 x 2652 pixels, 120 Hz | |
| Type | Color OLED Screen (1.07 B) | |
| Aspect Ratio | 19.8 : 9 | |
| PPI | ~429 PPI | |
| Touch | Yes, with Multitouch | |
| Features | HDR10, DCI-P3 wide Color Gamut | |
| Main Camera | Honor 80 Pro Plus | other phones |
| Camera | Punch Hole 50 MP f/2.4 (Wide Angle) | |
| Flash | Yes, LED | |
| Features | HDR, Panorama, Time-Lapse Photography, AI Photography, Night Scene Mode, Portrait mode, | |
| Video | 4K | |
| Selfie camera | Honor 80 Pro Plus | other phones |
| Camera | 200 MP f/1.9 (Wide Angle)
50 MP f/2.2 (Ultra Wide)
8 MP f/2.4 with autofocus | |
| Video | 4K, 1080p | |
| Connectivity | Honor 80 Pro Plus | other phones |
| 3G Network | Yes | |
| 4G Network | Yes | |
| 5G Network | Yes | |
| Bluetooth | Yes, v5.2, A2DP, LE, aptX HD | |
| EDGE | Yes | |
| GPRS | Yes | |
| GPS | Yes, with A-GPS, GLONASS, BDS | |
| USB | Yes, USB-C v2.0 | |
| Extra | NFC | |
| USB Features | USB on-the-go, USB Charging | |
| VoLTE | Yes | |
| Wifi | Yes, with wifi-hotspot | |
| Multimedia | Honor 80 Pro Plus | other phones |
| 3.5 mm Jack | No | |
| Battery | Honor 80 Pro Plus | other phones |
| Type | Non-Removable Battery | |
| Battery capacity | 4500 mAh, Li-Po Battery | |
| Fast Charging | Yes, 100W Fast Charging | |
| Reverse Charging | Yes | |
| Design | Honor 80 Pro Plus | other phones |
| Dual Sim | Yes | |
| Sim Type | Dual Sim, GSM GSM | |
| Sim Size | Nano Nano SIM | |
| Features | Honor 80 Pro Plus | other phones |
| Sensors | Accelerometer, Gyro, Proximity, Compass | |
| Fingerprint Sensor | Yes, In Display | |
| Face Unlock | Yes | |
